Category Archives: Medical

Dagga usage among medical students in Johannesburg SAMJ 16 APRIL 1983

 

in 19831020 undergraduate medical students at the University of the Witwatersrand was surveyed in 1981 as regards attitudes to and patterns of illicit drug use 868 completed the questionnaire; 32,4% had tried dagga (cannabis) and 16,4% were still using the drug. There was a large increase in the number of students using the drug as they advanced through
their studies (6% of the 1st-year class as against 24% of the 5th-year class). The timing of dagga use and previous experimentation with habit-forming drugs· are mentioned, and reasons for non-experimentation· and attitudes towards legalization of dagga are analysed.South African Medical Journal

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DAGGA AND DRlVING BY THEODORE JAMES SAMJ 16 May 1970

 

 

Cannabis addicts regard the smoking of hemp as a ‘way of life’. – Theodore James 1969
45 years later the Dagga Movement reminds the world that: Dagga is a healthy lifestyle, not a drug. Dagga is a way of life, not a crime.

South African Medical Journal

This communication is concerned with a topic that has not yet been publicly discussed or expressed. It is the outcome of inquiry into the problems pertaining to the indulgence in dagga by our so-called permissive society which has erupted all over the world, bearing in mind the indigenous characteristics and culture of the different regions.

In The Times of 24 July 1967 a conglomerate group of scientists, doctors and intellectual types asserted that ‘the law against marihuana is immoral in principle and un­workable in practice’. This is one of the various declara­tions which have been uttered in recent years for the abrogation of much of the law and the associated ideas against the taking of cannabis or dagga.

In the summary of the report of the Advisory Com­mittee on Drug Dependence’ it was stated that ‘cannabis is a potent drug having as wide a capacity as alcohol to alter mood, judgement and functional ability’, and The Lancet,’ citing this summary, agreed that it is a dangerous drug in that particular respect.

The purpose of this paper is to stress the considerable danger inherent in that ‘alteration of mood, judgement and functional ability’, and the driving of a motor vehicle. I know of no conviction for dangerous driving while ‘under the influence’ of dagga, but the reasons for this are pretty obvious. It is difficult enough to bring in a verdict of dangerous driving while under the influence of alcohol, without thrusting this infinitely more difficult proof upon the shoulders of the public prosecutor. Never­theless, the possibility, even probability, of such a com­bination of circumstances justifies its consideration.

It is not my wish to mention the pros and cons of dagga smoking, but some of the effects of dagga smoking upon human beings need to be described in order to appreciate their relationship with the act of driving a motor car. With all pious moralizing put aside, the grave nature of this relationship will disclose itself. Let it be acknowledged openly that the drug is able to excite unmixed pleasure when used moderately. Johnston3,. described its use as producing ‘an increase of pleasure’; it is ‘the exciter of desire, the cementer of friendship, the laughter-mover, and the causer of the reeling gait’. That was written 115 years ago. More detailed impressions have been forthcoming since his time and the sensory perceptions which are most commonly experienced and which have a direct bearing upon my topic are those which Thomas de Quincey so admirably expressed to convey his sensations after eating opium: time lengthens to infinity and space swells to immensity. These altered perceptions are very real to the dagga smoker of almost any type of character or temperament. Exaggeration is the cardinal manifesta­tion of most of the perceptive illusions when they are experienced. But exaggeration also expresses itself in the overt behaviour pattern which is derived from the basic character and temperament of the user of dagga. This is important in that the drug removes the veneer of conditioned civilized behaviour of an individual and exposes true character and temperament. If one be meek and mild the influence is to exaggerate this characteristic to inane bonhomie and fatuous friendliness. But if aggressiveness be the foundation-stone of his character which also evokes hostility, then quarrelsome and contentious is likely to be his pattern of behaviour. To the simple, primitive herds­man with his flock of sheep a pleasure derived has been the apparent large increase of his flock; whereas to the desert-dweller the pool of muddy water at the bottom of the wahdi has appeared to his magnifying eyes as the Selima Oasis.

The prolongation of seconds into minutes, minutes into hours, and hours into days is a remarkable but unexplained subjective cerebral phenomenon. Certainly, short periods of time are extended without any relationship with the actual passage of time, and such a disassociation of sub­jective awareness of time and actual time when the driver is under the influence of dagga, could be life-taking. There seems to be all the time in the world to carry out the particular manoeuvre indicated by the emergent cir­cumstances in which the driver finds himself, but in fact there are only a few seconds. This fact with its attendant hazards speaks for itself.

The other subjective and vivid awareness of a pro­longation and expansion of spatial dimensions can bring with it attendant danger. Two optical sensory fallacies, opposite in their direction, may occur but not in the same person during one episode of intoxication. One is the false impression of near objectives being seen very clearly at a far distance, and the other is exactly the reverse impres­sion-objects far away are like those pinpointed by the cine-camera and ‘zoomed’ within a second or two to within a few feet of the viewer. Whichever optical illusion is excited by the drug, the dangers involving the drugged driver also speak for themselves.

There are one or two important factors related to the use of dagga in the circumstances under discussion, and these are pharmacological facts. If the dagga is taken as smoke, the effects, if they are to be produced in the parti­cular individual (for much depends on the personality of the smoker and the quality of the dagga), will show them­selves in a few minutes. If this be the case and the quantity inhaled from a ‘good’ dagga cigarette is enough, it will be able to continue exciting the senses for as long as 9 hours.’ How an individual will respond to the intake of dagga in this manner is unpredictable at the start, and even afterwards his behaviour may be modified by his mood and state of health. It is unusual for 2 or more smokers to respond similarly to the same cigarette.

It is not uncommon for the effects of alcohol and dagga to be compared, but this comparison can be faulted. The likeness is superficial only. Alcohol induces a contraction of the personality and is essentially a de­pressant and not a stimulant, whereas dagga is curiously enough both stimulant and depressant but in different areas. Dagga does produce drowsiness and even sleep if the smoker be left undisturbed, but it is also capable of astonishing augmentation of physical strength. What is known about the time of onset and the duration of these pleasurable sensations is significant where driving a car is concerned. To drink alcohol to the blood-level of care­lessness is not necessarily a long undertaking and if this is followed by the drinker driving a car, then he does so with all his senses blunted as well as a degree of defective muscular co-ordination. Alcohol per se does not stimulate agreeable sensory perception, which dagga does, but by removing inhibitions it apparently expands the drinker’s personality. Dagga in moderation need not inco-ordinate the neuromuscular system; but it does falsify impressions to render them enjoyable, and this is where dagga and the driver become a dangerous combination. But dagga plus alcohol in the driver is even worse.

Although the taking of dagga, in South Africa almost always by smoking, is an illegal act in this country, the control of the drugs is extremely inadequate-if legal prose­cutions and convictions running into many thousands per annum are any indication (see below)-and it has be­come ‘permissive’ among the White ‘t~lite’ male youth of this country, whereas not so long ago it was only the ‘poor whites’ and non-Whites who were dagga smokers. Now­adays not only is it ‘permissive’, but among our younger citizens you are simply not ‘with it’ if you are not sociable enough to join in such delightful group activities! Any young man of 18 or so years of age, able to vote and drive a car, could, if he would, tell of friends or asso­ciates of his who indulge in the weed. High schools, colleges and universities have their habitues.

CONCLUSION

I have no recent figures for prosecutions and convictions for the crime of being in the possession of dagga, but 21 years ago the breakdown of convictions for this crime for the whole of the Union as it then was, was as follows:’ Whites 185, Coloureds 2 950, Bantu 10676 and Asiatics
205. It is most likely that the culprits were those resident in or near urban areas. There is no valid reason to believe that any diminution in the number of prosecutions and convictions-which 2 groups of civil offenders are prac­tically identical-has taken place over these 21 years, and there is every reason to believe that with a rapidly grow­ing population of all ethnic groups, together with a rise in the general standards of living, at a time when there is a strong drive for leniency or even condonation of erst­while misdeeds, the incidence of dagga smoking has in­creased enormously. As the pedlars might say, ‘It’s been good for trade’. Cannabis addicts regard the smoking of hemp as a ‘way of life’.

SUMMARY

An attempt has been made to draw attention to a very probable lethal factor which could well be emerging onto our motor highways and prevalent mainly among our youth rising to manhood. This is the so-called ‘permissive’ smoking, although illegal, of dagga, marihuana, hashish, ‘pot’, ‘grass’­call it what you will. No solution to this probable problem is proposed; it is felt that an awareness of such a threatening situation will go some way towards its mitigation. An un­loaded gun is no more lethal than a walking-stick. A ‘loaded’ driver of a motor car is dangerous indeed.

REFEREFRCES

  1. Advisory Committee on Drug Dependence (1969): Summary of Report on Cannabis. London: H.f\.1. Stationery Office.
  • Leading Article (1969): Lancet, 139.
  • J. F. W. (1855): Op cit.’
  • Baker-Bales, E. T. (1935): lancet. I. 811.
  • Interdepartmental Committee on lhe Abuse of Dagga (1952): Union of South Africa Reports W.G. No. 31.

‘Date received: 26 November 1969.

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DAGGA – A REVIEW OF FACT AND FANCY. Theodore James SAMJ 16 May 1970

 

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‘Dagga’ is our word for marihuana, hashish, bhang, or Cannabis sativa L. But dagga is also the name applied to 14 species of the plant leonotis, indigenous and common in South Africa.1 The word has come into our English language via Afrikaans which derived it from pure Hotten­tot ‘daga’. It is only assumed that the idea in the Hotten­ tot mind which attached the word to the plant cannabis had to do with its remarkable qualities.

The fact that the name dagga refers to both cannabis and leonotis, 2 plants growing wild and readily in South Africa, has in the past given rise to much confusion among those who have interested themselves in the ‘dagga pro­blem’. This confusion appears to be’ based on, or originate primarily from, the superficial similarity of appearance of the two species of plant, and different people hold different opinions about which species is the ‘true’ dagga. The confusion is confounded still more by the properties which some writers have attributed to leonotis, compara­ble with those of cannabis, but which have been denied by others.1 An editorial in the Journaf during the editor­ship of Leipoldt, always an interesting controversialist, held that leonotis was the ‘original dagga’ but conceded that usage appeared to have firmly attached the name to cannabis, and for this reason we have been obliged to accept the word dagga in this relationship.

Watt and Breyer-Brandwijk,l the eminent botanists, regard cannabis as the ‘true’ dagga. These 2 authors, as a result of their investigation into the properties of the 2 plants, concluded that the smoking of leonotis ‘produced no symptoms apart from unpleasantness’.'” But contrarily, Die Ajrikaanse W oordeboek4 states unequivocally on its own authority ‘die rook van die blare en jong stingels dieselfde bedwelmende uitwerking het as by bogenoemde soorte (Cannabis)’ but which can be differentiated from the latter by such names as kaffer-, klip-, knop-, koppies-, malkop-, perde-, rooi(pootjie)-, strand-and velddagga.

Here we have 2 apparently ‘authoritative’ but contra­dictory statements about the potential intoxicant proper­ties of leonotis, and Watt and Breyer-Brandwijk have studied one variety of this series as far as the botanic minutiae are concerned but not with regard to the chemi­cal properties. The practical evidence, however, indicates that leonotis is not the species of plant which is smoked in South Africa for enjoyment, because all of 93 speci­mens produced in court in police prosecutions were with­out exception cannabis -indirect but acceptable evidence that it is dagga cannabis and not dagga leonotis which is smoked for the hedonistic pleasure it provides the smoker.

The fact that cannabis is prohibited by law in this country while leonotis may be freely grown, and that all convic­tions have been for the possession of cannabis, speaks volumes against leonotis having any of the virtues or vices of cannabis.

If we go back to the Hottentots’ practice of using dagga we can take it that the first description written in Southern Africa on the effects of cannabis was that by Governor

‘Date received: 26 November 1969.

Jan van Riebeeck ln his diary. He observed: ‘De Hau­cumguas, welcke. . . mede lantbouwen, daar se daccha in teelen, sijnde een droogh cruijt dat de Hottentoos eeten ende droncken van worden.’ It is of some interest to note that Van Riebeeck used the word eeten and not rooken!

HISTORICAL RETROSPECTION

Van Riebeeck’s diary informs us that the consumption of dagga was a well-established ‘way of life’ among the primitive Hottentots of the Cape before his arrival, ~~d this fact raises interesting speculation about the ongm of the habit among so aborjginal an ethnic group (Bush­men were also partakers of the weed) here at the southern­most tip of Africa, a custom that can be traced back to ancient times in the Middle East.

The plant has considerable agricultural and commercial importance, derived from the manufacture of fibre and oil for soap and oil-cake (which facts in themselves deter­mine that the common hemp will always be with us). The surmised route for the propagation of the plant is, or was, along the ancient ocean highway from the eastern Mediterranean along the Red Sea and southern coasts of Asia to the shores of Hindustan–one of the oldest routes along which migration of races took place in olden time~”

The presumption that the Hindi word bhang (cannabis) is the root of the Shangaan word mbangi, meaning dagga, has been justified. The implication extracted from this obvious identity of the 2 names for dagga, in 2 languages which have absolutely no etymological point of contact, is that the plant was first carried to the coast of Mozam­bique, which is the region of East Africa where Shang~an is spoken, by the Portuguese militant trade~s returmng from India (Cannabis sativa L. lndica). There It was plant­ed and thence spread by name and proliferation inland and southwards to reach the Venda people in the Soutpansberg of the Southern Transv~al, in~o whose .lan­guage it insinuated itself as mbanzhe (m whic? the Hindu origin can still be detected).’ But the tranSIt from the Venda to the Zulus of Natal substituted the name intsangu, and this in turn was replaced by dagga when it reached the Hottentots.

Other early observers along with Van Riebeeck have recorded the smoking of dagga by all the races of Southern Africa, Hottentot, Bushmen and Bantu. These indigenous inhabitants still adhere to the tradition that their ancestors have used dagga since time began, and so it is not possible to know how or when the custom of its social usage was introduced into any particular tribe.

This social usage among the Bantu is deserving of some additional comment if only to indicate the tribal and patriarchal approval of the practice among a people, like the Zulu, who are essentially a warrior-race. Very few Bantu women-with occasional exceptions among the elderly-smoked dagga and this temperance has been attr~­buted to, but not adequately explained by, 2 tribal condI­tions: firstly, the payment of cattle by the husband as lobola for their wives, who were expected to render full service in return, did not encourage such a ‘luilekkerland’

habit among the womenfolk; and, secondly, the fact that as the women had to do the routine work of the tribe there was no time for this kind of idleness.” In times past the bad effects of excessive dagga smok­ing, as with all excesses, were recognized for what they were, and immoderate use of the weed was despised by the elders of the tribe. Accustomed smokers used dagga in moderation and in somewhat formal fashion; intemper­ance was frowned upon then, and probably, among the rural Bantu, it is even now.”

THE DAGGA DOCTRINES

Presently when dagga is being subjected to legislative, sociological, pharmacological, thological, deontological and even philosophical inquisition in different parts of the world where ‘permissiveness’ is accepted as a new way of life, where established taboos have been displayed as unacceptable superstitions by youth crusading against ancestral authority, it is opportune to notice how the Bantu, who have indulged themselves for centuries in the drug, are convinced about the effect experienced with its use. Their views agree in great measure with those of repu­ table investigators in the western world who have been commissioned to evaluate the influence of its use upon society.

The Bantu believed and have observed that dagga affects different individuals differently. The effect is closely tied to the inborn temperament of the smoker (or eater) of dagga. They do not, despite the law’s opposition, regard the habit as reprehensible unless it be taken to excess.

The Zulu and Xhosa-speaking Bantu have not accepted the official White man’s thinking; they deny that anything harmful arises from the moderate use of dagga. Bryanf has recorded in his account of the Zulu people that ‘young warriors were specially addicted and under the exciting stimulation of the drug were capable of accomplishing hazardous feats’. Here was reason enough for the young bloods of the tribe! The Bantu, on the other hand, do not regard the plant as having any aphrodisiac qualities; pa­rents whose young nubial sons have shown little or no interest in taking a wife have blamed the disinclination on dagga.

Wolff’: in South America, where the taking of cannabis (marihuana) is regarded by the governing authorities as a national evil, tried out the effects of the drug on 50 non-selected individuals who were asked to smoke it in a convivial environment without let or hin­drance of any kind, and he was able to separate 14 different kinds of reactions. He was not able to predict the type of reaction which would follow the smoking of marihuana but he was satisfied that the reaction to the drug was capable of revealing the true or real nature of the smoker’s character and personality.

In his group of 50 non-selected cases, only 7 did not show aggressiveness. Wo!ff, contrary to the viewpoint of the Bantu mentioned above, asserts that marihuana does stimulate sexual propensity and can ‘produce the psychic state of a Don Juan’. And he had enough ‘observed material to demonstrate that marihuana can also create criminal attitudes and acts’. He is also of opinion that addiction leads to general mental deterioration.

The leaders among the Coloured people of South Africa lean strongly towards Wo!ff’s conclusion arrived at in South America, and disagree with the opinion of the Bantu in their own country. They recognize the dagga habit as the companion of poverty, the cause of backwardness and the accomplice of crime; all these leading to unemploy­ment and disregard of personal respectability. They see dagga as a symptom as well as a cause of these conditions.

But even here, among this population group with a long experience of the use of dagga, there is a -considerable school of thought which does not believe the substance to be harmful … in moderation. But they will concede that dagga and alcoholic drinks (which are usually potent) can produce a much more dangerous and intense intoxi­cation than either alone, and that the effects of the combination are always harmful.

The Commissioner of Police, mentioned in a report of the authoritative Interdepartmental Committee on the Abuse of Dagga: recommended the provision of severe penalties for any form of traffic in the drug and that an institution be established for the treatment of addicts. He believed the consumption of dagga to be an important contributing factor in the incidence of crime. Twenty-one years ago the number of convictions for being in the possession of dagga was 14016, of which 185 were Whites, 2 950 Coloured, 205 Asiatic and 10 676 Bantu. These were convictions all over South Africa in one year.” The charges were for one crime, that of being in possession of dagga in whatever form, not having committed crimes while under the influence of dagga. A sameness with a difference.

More than 30 years ago Bromberg’ studied the effects of cannabis upon a number of individuals, and although he talked of toxic marihuana psychoses and described the manifestations of this state in some detail, he nevertheless concluded that ‘countless persons use marihuana without the development of an observable mental condition. In the acute intoxication no permanent effect is observable by psychiatric examination after the effects wear off in 1-3 days.’ He found in general that early use of the drug apparently did not predispose to crime. ‘No positive re­lation could be found between violent crime and the use of marihuana in cases observed in the psychiatric clinic. No cases of murder or of sexual crimes due to marihuana were established.’ Bromberg also reported that the lack of increased tolerance and the absence of demon­strable symptoms argue against the theory that mari­huana is habit-forming and that the use of marihuana is a ‘sensual addiction in the service of the hedonistic ele­ments of the personality’.

Bromberg does not appear to have changed his view­point since his first publication, for Wo!ffs flatly contradicts his conclusions as being derived from ‘material scarcely adequate for such deductions’. The ‘material’ consisted of observations made in courts-of-Iaw, clinics and prisons, and ‘it is the nature of criminal tendencies not to mani­fest themselves in the hospital, nor in the outpatient department nor at the judicial cross-examination’. Nor did Wolff consider the ‘experimental conditions’ to be right for prisoners to be given marihuana to smoke in surroundings of rigid discipline instead of ‘the bad but free environment to which they are accustomed’. Wolff added a criticism of Bromberg’s article by stating that it appeared that Bromberg in an effort to combat wideIy­ held and perhaps alarmist views of the dangers of mari­huana had ‘leaned too far back and minimized the long­term noxious effects’. The same criticism that was levelled by Wolff against Bromberg’s investigation might be di­rected against a report of an investigation into the mental symptoms associated with the smoking of dagga conducted by the Commissioner for Mental Hygiene in South Africa and published in 1938.]0 For all the participants in the trial were inmates of a mental hospital who were suffering from 9 varieties of mental illness, ranging from pure dagga psychosis to manic depressive psychosis. Any con­clusions that may have been arrived at from this attempt must be considered invalid, and this despite the terms of reference reading ‘to arrange for a controlled investi­gation into the possible relationship of dagga-smoking with acute psychotic conditions and with the ultimate production of a state of mental degeneration in addicts’.

A scanning of the world press”,ll of the past 40 years r’eveals a remarkable constancy of lights and shadows which blur the truth about the use of cannabis. In South Africa around 1934 the daily press was critical of official opinion and made a case for the harmlessness of dagga smoking, pointing out its use among the Bantu where it showed no evidence of being habit-forming. The press’ appeared to disapprove of the fact that during the year ending in 1934, out of 5885 convictions under the terms of the 5th Schedule of the Medical, Dental and Pharmacy Act,Ll 5 878 were for the possession of dagga, the remaining 7 being for opium.

Yet, across the ocean in North America the Canadian Medical Association Journal” thought fit to devote an editorial that same year to the availability and effects of cannabis upon the youth of Canada, the drug having been smuggled in from the USA. It mentions that as long ago as f931 cannabis cigarettes were being passed to boys and girls. It referred to ‘the experience in all countries that hashish has a special appeal for the young, not that they crave the drug, at least at first, but they use it to appear “smart”. They have not at any time been addicts of morphine, etc.’ Another point made was that the drug has a peculiar fascination for certain types of character, and because there is no depression or nausea following its use, this becomes an added attraction. The Lancd” noticed tpis editorial and quoted that marihuana cigar­ettes were on sale in cabarets and night-clubs, were even hawked about to young boys and girls, and were peddled iD. dance-halls; and that the traffic in Indian hemp had attained the proportions of an industry with widespread ramifications. Opinion was also expressed that it was the heavy restrictions on the ‘hard’ drugs (heroin, cocaine) that induced the smoking of cannabis.

The New York Times” published an article on the ‘Increasing menace of marijuana’ in the same year. Ac­cording to the report there was little or no control exer­cised over the buying and selling of cannabis in the United States. There is no control today. So it cannot be justifia­bly said that circumstances pertaining to the traffic in dagga are any different, i.e. any better, or any worse; they are surely very much in statu quo.

The question arises: does enforcement or, rather, attempted enforcement of the law help? This leads us to The Times of London, which on 24 July 1967 published a very provocative statement signed by a set of scientists, doctors and intellectuals who urged that ‘the law against marihuana is immoral in principle and unworkable in practice’, and this was only one of many demands for more ‘permissive’ tolerance of the drug.” This modern attitude by quite influential people could have been a distorted echo of a leader in The Lancet'” in 1963 which suggested that the argument for legalizing the import and consumption of cannabis (in England) was worth con­sidering. The Lancet had occasion later to regret using the words ‘worth considering’, for all who read them took them to mean that The Lancet supported the legalization of the drug in England.

The British Home Office,” in 1967, made it known that some 97% of all heroin addicts known to the Home Office had a previous history of taking cannabis. In the British Houses of Parliament that same year the Under-Secretary for the Home Office” deprecated any suggestions that cannabis was not a serious question. He said that there was more traffic in, and consumption of, cannabis than any other drug under international control. Perhaps there is some significance in the fact that 2 countries with a vast experience of the smoking of cannabis, Egypt and South Africa, should separately and in different years have made special representations to the League of Na­tions on the subject of cannabis. In 1923 it was the express wish of South Africa that dagga be included in the list of narcotic drugs which, previously, had included almost only opium and its derivatives.s Two years later the Egyp­tian delegate to the second conference on opium of the League stated that 30 -60% of those patients suffering from insanity in Egypt were cases of ‘chronic hashishism’.’s

Bourhill,19 in 1913, submitted his thesis to the Univer­sity of Edinburgh on the evils resulting from the smoking of dagga among the native races of South Africa, and among the evils he included admissions of dagga lunacy to the mental hospitals. These lunatics were often danger­ous to person and property. The recovery rate was high but the frequency of relapses supported suspicion that the continued habit was liable to produce a chronic psy­chosis. Blair,'” writing on this aspect of dagga addiction, stated simply, ‘the cannabis smoker nearly always becomes an imbecile in time’.

A leading article in The Lancet’tl of January 1969 ap­peared to sympathize with a proposal to lessen the penal­ties currently imposed upon anyone connected with the illegal use of cannabis. The sympathy was activated by the summing up of a report on cannabis by the Advisory Committee on Drug Dependence,'” in England, which read, ‘Not withstanding the limits of present knowledge, it is clear that cannabis is a potent drug having as wide a capacity as alcohol to alter mood, judgement and func­tional ability. In that sense, we agree … that cannabis is a “dangerous drug.” But we think it is also clear that, in terms of physical harmfulness, cannabis is very much less dangerous than the opiates, amphetamines, and bar­biturates, and also less dangerous than alcohol.’ The British Medical Journal,” in an editorial entitled ‘Potted dreams’, came out strongly against this proposed lessening of penalties for a drug that ’causes mental disorientation’. The Lancet could not uncover any reports of persistent psychotic states following cannabis, and although acute psychoses are recognizable and usually pass away un­eventfully, the existence of a persistent ‘cannabis psychosis’ was regarded as doubtful.” Is it possible to reconcile some or all of these conflicting points of view?

THE INFLUENCE

The ‘official’ influence last appeared in the British Phar­maceutical Codex of 1949,” for the monographs on canna­bis have been omitted from the later editions. After a discussion of the nature of the constituents of the herb it elaborated thus: ‘Cannabis depresses first the higher critical faculties and later perceptive sensory and motor areas of the cerebrum. In some persons, particularly orien­tals, it produces a type of inebriation with a feeling of pleasurable excitement and some mental confusion, fan­tastic or erotic hallucinations and a loss of the ability to estimate time and space; later decreased sensitiveness to touch and pain, as well as muscular lethargy and relaxa­tion precede the onset of a comatose sleep in which respi­ration is slowed and the pupils are dilated. In other per­sons it may cause only lethargy with some irritability of temper. Cannabis is a habit-forming drug and habitues often become insane; amongst orientals it is taken as a drink or conserve or smoked in pipes or cigarettes under the names of chavas, ganjah, guaza, bhang, and hashish; in South Africa it is smoked under the name of dagga and in Mexico and Brazil it is the active ingredient of marihuana cigarettes. Cannabis is too unreliable in action to be of value in therapeutics as a cerebral sedative or narcotic and its former use in mania and nervous disor­ders has been abandoned.’

Nearly all the published work dealing with the intoxi­cant effect of cannabis upon people treats the subject on a generalized basis, and on these generalizations formulated from studies conducted on groups of people grossly differ­ent in culture, character and temperament, ethnic origins and physical and intellectual development, are erected moral injunctions and legal prohibitions. There are very few recorded first-hand clinical observations and assessments in our medical literature presented as case histories and none in South African medical literature, which is sur­prising for a country with such a long experience with the drug. It may be partly explained, perhaps, by the legal restrictions upon its enjoyment.

Dr Elizabeth Tylden,” however, had reason to write of her experience over many years of use of the drug, both at her childhood home in the Orange Free State and present­ly in England. She describes some of the smokers of hemp on her farm in the Orange Free State as being what today would be called, in the vernacular, ‘potheads’ and being ‘stoned out of their minds’. This was the result of constant dagga smoking and, in our vernacular of long standing, a ‘ware daggakop’. She has detailed histories of 40 addicts and is able to document the deleterious influence upon character with a change in personality. Her addicts, whom she called her chronic patients, looked ill and were ema­ciated despite enormous appetite and thirst. A significant observation which she makes from her sad experiences with consumers of the drug is that she dreaded ‘a crop of cannabis psychosis to supplement the diminishing men­tal hospital population’.

Thirty-five years ago Fleming’· had clinical experience of a ‘new’ case of acute dagga psychosis which was pre­ sented by Baker-Bates,” with detailed clinical appraisal of the condition as it manifested itself in a healthy young woman with an English cultural background. It arose in a curiously interesting fashion. A young man who had grown his own cannabis plant at home (having obtained the seed from a quantity of parrot food) made a cigarette from the flowering plant which he smoked out of pure curiosity originating from his reading on the subject. His delightful loss of sense for actual time and space dimen­sions, his vivid dreams or hallucinations and subsequent drowsiness proved of such interest to his fiancee that her curiosity was aroused, for she was incredulous of her fiance’s experience. She tried two-thirds of a cigarette made from the top of a fruity plant.

Soon afterwards she fell asleep and a few minutes later, when disturbed, awoke with a start and showed apprehension.Her eyes were bright, her hands were twitching, and she appeared intoxicated. She asked where she was, probably being deceived bv hallucinations, but seemed happy. Fifteen minutes later she \vas taken for a short walk which was interrupted by outbursts of laughter and of affection. Her speech becameslurred from dryness of the mouth and her gait increasingly unsteady. Twenty minutes later she was taken to a doctor who recorded that she was pale, but able to stand and walk, although feeling dizzy. She was very excited and talkative and made stiff purposeless movements with her hands. She was highly emotional towards her companion; at one moment gay, she was next anxious and said she felt ‘enclosed’. She exag­gerated the passage of time and was confused about spatial dimensions. Her tongue and mouth felt parched and words were pronounced with difficulty while sentences lapsed into incoherencies. Her eyelids were half-closed, while the pupils dilated but reacted to light. The pulse was rapid but strong. At 11 p.m. (50 minutes after smoking the cigarette) she was in a collapsed condition. Her symptoms were then loss of powerin her legs and inability to stand. Dizziness, dryness of the mouth and palpitation and lengthened estimations of the passage of time continued. She believed her condition had lasted for many hours and although she was fully conscious of her existence she imagined she was ‘outside her own body’, a hallucination of dual personality, enclosed in a small space and surrounded by a mist from which she could not escape. This imaginary mist did not impair her vision for distant objects. Examination also showed her speech to be confused, rambling, and often inarticulate. She was unable to stand steadily without support and showed great inco-ordination ofmovements of the hands. There was tachycardia (l40jmin) and also marked inspiratory dyspnoea. No other abnormality was found. She was treated in a general manner for ‘shock’ and sherecovered after 9 hours, when there was no sequela other than a severe headache.

This is the practically verbatim case report published in The Lancet. Its meticulous detail in a case of cannabis acute intoxication has not been matched in any publica­tion in our medical literature. And this was the outcome of smoking two-thirds of a dagga cigarette made from the fruit of a cultivated plant, a true Cannabis sativa L.!

CANNABIS AND ALCOHOL

These two drugs are often compared but the resemblance under close observation of the 2 forms of intoxication is only superficial. A brief description of the effects of im­bibed alcohol on the human being, written 150 years ago,:S cannot be improved upon. The pleasure given by alcohol is always rapidly mounting, and tending to a crisis, after which it as rapidly declines. In comparison the effect of cannabis (when of good quality), once effective, remains stationary for 8 -10 hours. The first is a case of acute, the second of ‘chronic’, pleasure; the one is a flickering flame, the other a steady and equable glow. Wine disorders the mental faculties. Cannabis enables one to say sharp and witty things. Pleasant ideas flit through the mind with a wonderful rapidity, so that time seems much extended. Alcohol robs a man of his self-possession. Cannabis taken moderately reinforces physical strength. Alcohol ‘unsettles the judgement, and gives a preternatural brightness and a vivid exaltation to the contempts and the admirations, to the loves and the hatreds, of the drinker’. Cannabis produces a pleasurable sensation of mild intoxication and the smoker or eater is particularly gay, joyous and pleased with everything. He will laugh and smile on the slightest provocation. Both give ‘an expansion to the heart and the benevolent affections’; but cannabis does not, as with alcohol, give rise to ‘the sudden development of kind­heartedness, always more or less of a maudlin and a transitory character, which exposes it to the contempt of the bystander. Men shake hands, shed tears, and swear eternal friendship-no mortal knows why; and the animal nature is clearly uppermost. True it is that even wine up to certain point, and with certain men, rather tends to exalt and to steady ‘the intellect … it may advantageously affect the faculties, brighten and intensify the consciousness and give to the mind a feeling of ponderibus librata suis.’

However, there is this likeness that alcohol and cannabis can both show a man’s true character. Alcohol, however, will ‘constantly lead a man to the brink of absurdity and extravagance; and beyond a certain point, it is sure to volatilize and to disperse the intellectual energies. A man who is inebriated, or tending to inebriation, is, and feels that he is, in a condition which calls up into supremacy the merely human, too often the brutal, part of his nature.’

There is this other very marked difference: Alcohol is notorious for that extremely unpleasant state of mental and physical distress which in the vernacular goes by the name ‘hangover’, which can vary considerably in its unhappy manifestations according to the types of alcohol imbibed and other associated means of raising the spirits. Cannabis, on the contrary, wiU permit the user to awaken refreshed even though his surroundings may feel unreal for an hour or so. There is usually no headache. An ex­cellent appetite is a common sequel.

DISCUSSION

Although in South Africa very little has been published in the medical journals about the clinical aspects asso­ciated with indulgence in dagga, its age-old and wide­spread use in certain sections of our population has evolved an argot about itself that is, perhaps, more in­formative of its short-term and long-term effects than any number of controlled studies.

Regular smokers recognize a good-quality dagga by its smell and by rubbing it with the fingers, and for this they will pay high prices. They know also that ‘good’ dagga is only produced in certain areas where both heat and a good rainfall favour abundant growth and tran­spiration with consequent concentration of resins in the leaf.” This is of gre~t meaning and it demands serious consideration by all those who may be concerned in assessing the harmlessness or evils in connection with cannabis. Woltr was astutely aware of these factors when he was investigating the plant in South America and Brazil. He said its ‘action is destructive of both character and intelligence’ but only after recognizing that any ‘delirium’ depends upon the concentration of the drug according to its locality of growth and on the sufficiency or not of the resin in the plants due to particular climate and soil. This I believe to be the nub of the disagree­ments and inconstancy associated with experience, thoughts and opinions about cannabis. It is grown all over the world in different climates and soils, and from all over the world we get different reports and impressions of its effects upon human beings. Hence we get comments made such as ‘hashish has been in general use among Eastern peoples as a means of producing ecstasy from remote antiquity”” but in that part of the world the user takes the dried flowering tops of cultivated female plants which are coated with resin (gunjah or ganga), or the resin he scrapes off the leaves or the dried leaves them­selves, and as with the hashish eaters of the Middle East (persia, Arabia, Egypt) the resin is compounded into a flavoured sweetmeat or syrup. This method of ingestion acts somewhat differently from smoking. With high dosage extraordinary feats of valour, derring-do, or running amuck become manifest, for it was in this way that the assassin sect at the time of the early Crusades excited their devoted exterminators to remove unwanted individuals, their zeal for the job being heightened by the consumption of the drug.

If the drug be taken by mouth, absorption is greatly aided if it is taken an hour before a meal. Its action is then felt within 2 hours. If it is taken after a meal no result may be detectable for as long as 6 hours. Of the com­bined effects of stimulation and depression of the cerebral cortex when the drug is taken by mouth, it is the latter effect which is said to predominate’·

In South Africa the general custom for seeking a degree of intoxication has for long been that of smoking the herb. A method popularly practised before legal prohi­bition, but now only occasionally, was to smoke it through water held in the mouth, or kept in the dagga pipe, hence the expression ‘die daggapyp laat gorreI’. Bantu, Bushmen, Hottentots and Coloureds used essentially the same method. By drawing the smoke through water in a pipe the smoker does not have to hold water in his mouth, the objective being to cool the fumes; an accompanying physical change is a condensation of the volatile active principle before it enters his lungs. Prohibition has ren­dered this method not readily practicable, for it demands relaxation and leisure; one result of this is to make the smokers draw harder on pipe or cigarette, and faster, so generating more heat and volatilizing more of the principle to enter their lungs.”

Besides the quality or effectiveness of the plant varying greatly according to the environmental conditions of climate, soil, season and so on, as mentioned the state of the individual smoking it is also of much importance. There is considerable variation of cannabis” and consider­able variation of personality; the variety of combination of the 2 factors appears to produce a variety of symptoms’ or states of euphoria. There is a striking similarity here with opium. ‘The varieties of the effect produced on different constitutions are infinite.”s It could well be this
factual variety of response to the intake of dagga that may have something to do with the variety of impressions which have been uttered. Cannabis is reputed to cause
sexual excitement, but there are many who deny this; if there is evidence of sexual excitement the psychological make-up of the smoker probably has much to do with
it. The lack of inhibition induced by the drug’s erotic charm and images may be conducive to this effect.

SUMMARY
This is a review of practically all the factors both real and unreal which appear to motivate the opinions and actions of many enquirers and authorities who are concerned with the
growing world menace of drug addiction, but with dagga in particular. The conclusions arrived at by special investigators and committees about the effects of dagga on the human being
are that, in the main, they are detrimental to man, physically, mentally, and morally; that if it does not produce psychotic states it does produce very definite moral deterioration. If
these conclusions are accepted on the evidence available by controlling governmental authority they could well find critics who also, on the evidence available, could declare that the
conclusions are too rigid and even exclusive of facts which should be seriously considered before any legislative action is introduced.

DAGGA AND DRlVING

This communication is concerned with a topic that has not yet been publicly discussed or expressed. It is the outcome of inquiry into the problems pertaining to the indulgence in dagga by our so-called permissive society which has erupted all over the world, bearing in mind the indigenous characteristics and culture of the different regions.

In The Times of 24 July 1967 a conglomerate group of scientists, doctors and intellectual types asserted that ‘the law against marihuana is immoral in principle and un­workable in practice’. This is one of the various declara­tions which have been uttered in recent years for the abrogation of much of the law and the associated ideas against the taking of cannabis or dagga.

In the summary of the report of the Advisory Com­mittee on Drug Dependence’ it was stated that ‘cannabis is a potent drug having as wide a capacity as alcohol to alter mood, judgement and functional ability’, and The Lancet,’ citing this summary, agreed that it is a dangerous drug in that particular respect.

The purpose of this paper is to stress the considerable danger inherent in that ‘alteration of mood, judgement and functional ability’, and the driving of a motor vehicle. I know of no conviction for dangerous driving while ‘under the influence’ of dagga, but the reasons for this are pretty obvious. It is difficult enough to bring in a verdict of dangerous driving while under the influence

‘Date received: 26 November 1969.

of alcohol, without thrusting this infinitely more difficult proof upon the shoulders of the public prosecutor. Never­theless, the possibility, even probability, of such a com­bination of circumstances justifies its consideration.

It is not my wish to mention the pros and cons of dagga smoking, but some of the effects of dagga smoking upon human beings need to be described in order to appreciate their relationship with the act of driving a motor car. With all pious moralizing put aside, the grave nature of this relationship will disclose itself. Let it be acknowledged openly that the drug is able to excite unmixed pleasure when used moderately. Johnston3,. described its use as producing ‘an increase of pleasure’; it is ‘the exciter of desire, the cementer of friendship, the laughter-mover, and the causer of the reeling gait’. That was written 115 years ago. More detailed impressions have been forthcoming since his time and the sensory perceptions which are most commonly experienced and which have a direct bearing upon my topic are those which Thomas de Quincey so admirably expressed to convey his sensations after eating opium: time lengthens to infinity and space swells to immensity. These altered perceptions are very real to the dagga smoker of almost any type of character or temperament. Exaggeration is the cardinal manifesta­tion of most of the perceptive illusions when they are experienced. But exaggeration also expresses itself in the overt behaviour pattern which is derived from the basic character and temperament of the user of dagga. This is important in that the drug removes the veneer of con­ (Continues in another document)

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Neuroscience Researcher Needs Young Heavy Smoking Volunteers for Study:Umcwaningi Udinga Ababhemayo!

I’m an acoustical neuroscience researcher, I’m looking for adult volunteers who are heavy smokers or substance users (one of 2 substances: whoonga or cannabis), and also those who have quit smoking these substances and who have been clean for 6 months or longer (i.e. who have completed their rehabilitation program), to be tested as part of my research studies EXPLORING EFFECT OF SMOKING HEAVILY ON BRAIN FUNCTIONING. All subjects (i.e. volunteers for testing a research study) must be healthy, and will be paid a stipend (R50-R200) for their participation in this research for about 2-4 days per person (+-2hrs each day)! SMS must answer all the questions & include your true email address so I could email you a preliminary questionnaire/form to complete & sign and then return to me: SMS the info: (i) your date of birth=current age (Example: I was born on 15 Jan 1995=19yrs old now),  (ii) sex/gender,  (iii) highest educational attainment=total number of years of formal schooling, (iv) area where you live, and (v) full/true name of substance/drug you have been smoking for at least 3 years non-stop (i.e. substance you smoke heavily without any control to stop) or drug you have just been rehabilitated to stop using/addiction to, to 0715286665. ALL YOUR ANSWERS MUST BE TRUTHFUL! Your info will be kept confidential and will not be passed to any 3rd party, only the researcher will know your real name & surname.

research-dagga-whoonga

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This is a scientific research for university degree and scientific journal publication that never reveal real names of research subjects [ONLY THE RESEARCHER’s FULL NAMES & HIS or HER UNIVERSITY ADDRESS ARE MADE PUBLIC], who are ONLY INCLUDED UPON SIGNING INFORMED CONSENT AGREEMENT FORM (to be given later on your 1st day/interview day). Lokhu wucwaningo lwesayensi lweziqu zasenyuvesi kanye nokushicilelwa kwijonali yocwaningo lesayensi engalinge iveze amagama angempela abantu abathestiwe ocwaningweni [YIGAMA LOMCWANINGI kanye NEKHELI NENYUVESI YAKHE ANEKELWA IZWE], okuqalwa nokuthi basayine okubizwa nge-INFORMED CONSENT (ngosuku lokuqala/lwenhlolokhono). ***Advert kept on file=Isikhangiso silondoloziwe!

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Time to extend pockets of excellence in fight to beat cancer BY WILMOT JAMES

MARIJUANA has properties that moderate pain. Its use brings relief to cancer sufferers, as brought into focus recently by the tragic death of Inkatha Freedom Party MP, Mario Oriani-Ambrosini. Marijuana does not prevent cancer, nothing does. It is most likely the most intractable unsolved medical science problem of our day. Neither does it replace existing medical interventions such as surgery, radiation, chemotherapy or viral-based therapies that in certain defined instances can break down tumours after the cancer has taken hold.

Melanoma treated with dagga oil

No matter which marijuana strains are used, it bears repeating that it neither prevents nor therapeutically is capable of treating cancer. Depending on how far the cancer has spread, marijuana’s greatest benefit is to reduce pain and then only up to a point. In this respect it is uncontroversial if pain moderation (and other possible) properties are clinically verified, its use should be decriminalised for medical use. To do so does not require the commercialisation of production or distribution of marijuana.

These aspects are, as a matter of fact, not relevant in the least to the thrust of what needs to be done with the Medical Innovation Bill (a private member’s bill) introduced initially by Oriani-Ambrosini. Marijuana can be obtained by special dispensation, or it can be specially grown on experimental farms under the watchful eye of, for example, the Agricultural Research Council. Marijuana supply is a wholly separate issue from its appropriate medical use. This is why we propose that the issue of commercialisation of marijuana should be stripped from the bill.

In any event, we should not fixate on marijuana only. There are other plant-derived applications too. Though he overstates his case, Daniel Webster (in Botanical Oncology, 2014, Panaxea Publishing) provides considerable detail on well over 200 botanical health applications that may provide some benefit to cancer sufferers: “Many botanical substances,” Webster writes, “have good anti-inflammatory properties, can increase healing and stimulate immune response … botanicals have extensive properties to manage side-effects, overcome multidrug resistance and even increase the efficacy of chemotherapy.”

Of course, all these hypotheses should be subject to rigorous clinical scrutiny. But even if they were to pass the tough tests of clinical medicine, it must be said that plant-derived applications have some relevance when it comes to treating, but are not in the least significant when it comes to the real war involved in solving the problem of cancer.

To solve the cancer problem, requires a breakthrough in science that for now has proved elusive. That a breakthrough has not yet occurred gives no comfort to cancer sufferers, but that is no reason to give up on the scientific enterprise, which constitutes the only method in human history to generate consistently reliable therapies for many communicable and noncommunicable diseases.

Our understanding of what cancer is has advanced in leaps and bounds. In summary form, this is what we know about tumour cells and the onset of cancer (see Harvey Lodish et al, Molecular Cell Biology, 2012, chapter 24 Cancer):

  • Cancer is a fundamental aberration in the behaviour of cells. Most cell types of the body can give rise to malignant tumour cells.
  • Cancer cells can multiply in the absence of growth-promoting factors required for the proliferation of normal cells and are resistant to genetic signals that normally programme necessary cell death.
  • Cancer cells also invade surrounding tissues by breaking through the boundaries that define them and spreading through the body to establish secondary areas of growth.
  • Both primary and secondary tumours require the recruitment of new blood vessels in order to grow to a large mass.
  • Certain cultured cells infected with tumour-cell DNA undergo transformation. Such transformed cells share many properties with tumour cells.
  • The requirement for multiple genetic mutations in cancer formation is consistent with the observed increase in the incidence of human cancers as we grow older. Most of such mutations are not heritable.

While there have been major advances in integrating radio, chemical, genetic and botanical therapies, ongoing research is promising but has yet to yield prevention and curative breakthroughs. A noteworthy advance is gene therapy, but it is out of reach to most because at this time it is expensive and available only as part of clinical trials. Gene therapy is a treatment that involves altering the body’s genes (think of genes as “coding instructions”) to stop disease. Gene therapy replaces a faulty gene or adds a new gene in an attempt to cure disease or help our bodies’ ability to fight disease using existing immunity tools. It holds promise for treating cancer, cystic fibrosis, heart disease, diabetes, haemophilia and AIDS.

There are therefore compelling reasons to continue investing in advancing the science of cancer, chief among which is the ethical obligation to save human lives. It is in this respect that the Medical Innovation Bill should be redrafted to provide for a dedicated facility to co-ordinate existing and introduce new areas of research and treatment for cancers that tend to be most prevalent in the South African population.

During a recent visit to the biomedical research hub at Biopolis in Singapore, I was struck by how they, thinking and planning ahead, structured their high-level research to deal in an organised way with Southeast Asia’s disease burden, including cancers. Accordingly, Biopolis’s scientists have begun to establish the first stages in developing a therapeutic antibody pipeline by working with cancer stem, tumour-initiating and triple-negative breast cancer cells. They also developed a speciality in the early prognosis of gastric, liver and blood cancers in their populations of Chinese, Malaysian and Indian descent.

Even with lesser resources, thinking ahead, we should do the same here. We have pockets of excellence in cancer-related work at some of our universities, private hospitals, pharmaceutical companies and the Medical Research Council, but as an enterprise it is dissipated, unfocused, poorly resourced and without the right distribution of brain power. If nothing else Oriani-Ambrosini’s Medical Innovation Bill should focus our efforts.

• James is the Democratic Alliance’s shadow health minister